The Role of Instrumentation in the Healing Process of Spinal Tuberculosis: An Experimental Study

Introduction: Tuberculosis is still commonly found in many developing countries. Spinal tuberculosis can cause vertebral deformity and neurological disorders. It was discovered thousands years ago its management aimed to eradicate infection maintain the integrity of vertebrae. Previously, spinal TB using drugs external stabilization. Surgical techniques were developed afterwards clean infected segment. Because remained inevitable had impacts on disorders, new paradigm been by instrumentation stabilize segment restore function. TGF-? has a major role angiogenesis bone healing process. uses metal devices composed ions particles that interact each other so it could produce physical chemical energy transmitted The expected enhance biomolecular biocellular activity body's immune cells process be better.
 Methods: An experimental study carried out New Zealand Rabbits which given H37Rv strain body. Samples divided into five groups namely control rabbits, rabbits without intervention, treated instrumentation, anti-tuberculosis drugs. Then cytokine levels evaluated compared.
 Results: results showed significant TGF- ? level increase alone compared intervention. There who received only.
 Conclusions: Instrumentation improve increasing levels.